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Xeno - Free Medium Recombinant Human Serum Albumin Promoting CHO Cell Growth

Categories Human Serum Cell Culture
Brand Name: Oryzogen
Model Number: HY100M1
Certification: ISO9001 certificate
Place of Origin: China
MOQ: Negotiation
Price: Negotiation
Payment Terms: T/T
Supply Ability: 1000kg per year
Delivery Time: 3-5 days
Packaging Details: 1g/vial 10g/vial 50g/vial
Source: Rice Grain(Oryza Sativa)
Physical Appearance: Off-white to light beige lyophilized powder
Usage: Cell Culture, stem cell culture, vaccine reseach
EINECS No.: 274-272-6
PH: 6.4-7.4
Abnormal toxicity test: conforms
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Xeno - Free Medium Recombinant Human Serum Albumin Promoting CHO Cell Growth

Xeno - Free Medium Recombinant Human Serum Albumin Promoting CHO Cell Growth ​


Quick detail

  1. CAS No.: 70024-90-7
  2. Other Names: rHSA
  3. EINECS No.: 274-272-6
  4. Place of Origin: Hubei, China (Mainland)
  5. Model Number: HY100M1
  6. Purity: Greater than 99 % as determined by SDS-PAGE
  7. Endotoxin: Less than 0.25EU/mg
  8. Storage and Handling: Stored at temperatures 2-8℃ for 24 months

Physiological and Biochemical Properties of rHSA and pHSA

Char.pHSArHSA
Amino Acids SequenceSameSame
N-terminusDAHKSEVDAHKSEV
C-terminusKLVAASQAALGLKLVAASQAALGL
GlycosylationNoNo
Molecular Mass(MALDI)66.554KD66.550KD
PI4.84.8
Drug BindingSimilarSimilar
Thermal StabilityM/P 65℃M/P 65℃
Lipid ConjugationIdenticalIdentical
Crystal StructureIdenticalIdentical

Description

CHO was used as one of mammalian gene expression host cells, which has such advantages: high expression level, maintain the exogenous gene, suitable for the expression of a variety of proteins, convenient for separation and purification of downstream products, suspension culture, large scale of high-density culture. CHO cell is currently one of the most widely used mammalian gene expression host cells. Healthgen rHSA is animal component free and good batch consistency, which works as a kind of additive ingredient used in cell culture and much useful for the CHO cell research and production.


Advantages

1. Healthgen Biotechnology Corp. is a private company founded in 2006. We specialize in molecular pharmaceutical technology research and high-tech innovation-oriented product development, which is developing, manufacturing and marketing a series of recombinant proteins and growth factors by rice endosperm platform. We have 400 square meters of research center, in which 30% of the research personnels have doctoral degree and major in different directions of the research and development. Healthgen has strong capability in developing a series of biological products.


2. Healthgen recombinant human serum albumin is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.


3. Healthgen recombinant human serum albumin (rHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the rHSA, with the world's advanced facility and top production proceeding to extract and purify the rHSA, Healthgen can ensure the excellent consistency of rHSA from different batches. products.


4. Healthgen has a professional quality control department, in which 50% of them have master's degree or higher. There are 14 employees in the quality department, 9 of them are in QA and 5 are in QA. All of them have rich experience in analysis research or quality inspection. Half of them have graduated diploma. Every year there are more than 50 training courses, which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.


Supplemental Description

Human serum albumin has been widely used as plasma expansion reagent. Because of its non-enzymatic activity and no immunogenicity, etc. HSA can also be used as excipient and stabilizer in a variety of pharmaceutical preparations and serum-free cell culture medium component. In addition, HSA is also used as a drug carrier due to its antioxidant properties, thereby conferring drugs better physicochemical properties. At present, most HSA products in the market are directly derived and refined from human plasma.

On the one hand, due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by gene recombinant technology can effectlively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant DNA technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.

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