Home > Ester >

Anti-inflammatory ,analgesic,antirheumatic,antipyretic Diclofenac Sodium Injection 75mg/3ml 10 ampoules for I.M/I.V use

Categories Injection Medicine
Brand Name: Uni-pharma
Model Number: 75mg/3ml
Certification: GMP,ISO9001
Place of Origin: CHINA
MOQ: 30000 boxes
Price: USD0.25-0.30/box
Payment Terms: L/C, D/A, D/P, T/T, Western Union
Supply Ability: 10,000,000/Month
Delivery Time: 30 Days
Characteristic:: A clarity and colorless
Identification:: Positive reaction
pH: 8.3
ASSAY:C14H10Cl2N: 98.7%
Color of solution: pure
Specification: 75mg/3ml
  • Product Details
  • Company Profile
English
Français
Русский язык
Español
日本語
Português

Anti-inflammatory ,analgesic,antirheumatic,antipyretic Diclofenac Sodium Injection 75mg/3ml 10 ampoules for I.M/I.V use

Anti-inflammatory ,analgesic,antirheumatic,antipyretic Diclofenac Sodium Injection 75mg/3ml 10 ampoules for I.M/I.V use


COMPOSITION:
Each 3 mL contains 75 mg diclofenac sodium with 4% v/v benzyl alcohol.

PHARMACOLOGICAL CLASSIFICATION:
Antirheumatics (anti-inflammatory agents)

PHARMACOLOGICAL ACTION:
Diclofenac sodium has analgesic, anti-inflammatory, antirheumatic antipyretic activities. It is non steroidal. It is an inhibitor of cyclo-oxygenase. Diclofenac is metabolised in the liver to 4-hydroxydiclofenac and other hydroxylated forms, after glucoronidation and sulphation the metabolites are excreted in the urine (65%) and bile (35%).

INDICATIONS:
To be used as initial therapy for inflammatory and degenerative rheumatic diseases, as well as for painful conditions due to inflammation of non-rheumatic origin and acute attacks of gout.

CONTRA-INDICATIONS:
Patients with known hypersensitivity to diclofenac, or other non-steroidal anti-inflammatory medicines. Asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by acetylsalicylicacid, or other medicines with prostaglandin synthetase inhibiting activity. Diclofenac sodium is contra-indicated in patients with a history of active gastro-intestinal bleeding or peptic ulceration, or severe hepatic or renal impairment. Patients with porphyria. Safety during pregnancy and lactation has not been established.

WARNINGS:
Serious interactions have been reported after the use of methotrexate with diclofenac.

DOSAGE AND DIRECTIONS FOR USE:
Not intended for intravenous injection. Only for deep intragluteal injection into the upper quadrant. Seventy five mg by intramuscular injection once daily or twice daily in severe cases; each injection should be given at a different site. In renal colic the intramuscular dose of 75 mg may be repeated once after 30 minutes if necessary. Diclofenac ampoules should not be given for more than a few (2) days. If necessary, treatment can be continued with oral therapy.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Gastro-intestinal disturbances; reactions range from abdominal discomfort, nausea and vomiting, and abdominal pain to serious gastro-intestinal bleeding or activation of peptic ulcer. CNS-related side-effects include headache, dizziness, nervousness, tinnitus, depression, drowsiness and insomnia. Hypersensitivity reactions may occur occasionally and include fever and rashes. Hepatotoxicity and aseptic meningitis may also be hypersensitivity reactions. It can provoke bronchospasm in patients with asthma. It may cause cystitis and haematuria. It may also cause acute renal failure, interstitial nephritis, and nephrotic syndrome. Other adverse effects include anaemias, thrombocytopenia, neutropenia, eosinophilia, agranulocytosis, abnormalities in liver function tests, blurred vision, changes in visual colour perception, and toxic amblyopia. It should not be given to patients with active peptic ulceration. It should be given with care to the elderly, to patients with asthma or bronchospasm, bleeding disorders, cardio-vascular-disease, a history of peptic ulceration, and in liver or renal failure. Patients with congestive heart failure, cirrhosis, diuretic-induced volume depletion, or renal insufficiency are at greater risk of developing renal dysfunction due to NSAID-induced inhibition of renal prostaglandin synthesis. Care is required in those who are also receiving coumarin anticoagulants. Patients who are sensitive to aspirin or other NSAID's should generally not be given diclofenac. Diclofenac should be discontinued in patients who experience blurred or diminished vision, or changes in colour vision. Patients with collagen disease may be at increased risk of developing aseptic meningitis. In view of the product's inherent potential to cause fluid retention, heart failure may be precipitated in some compromised patients. When given together with preparations containing lithium or digoxin, diclofenac sodium may raise their blood concentrations. Patients receiving long-term treatment with diclofenac should have periodic blood counts. Studies have demonstrated a pharmacokinetic inter-action between diclofenac and salicylates when both are co-administered in anti-inflammatory doses.

KNOWN SYMPTOMS OF OVERDOSAGE AND ITS TREATMENT:
See "Side-effects and Special Precautions". Treatment is symptomatic and supportive.

IDENTIFICATION:
Clear colourless, to a pale yellow solution.

PRESENTATION:
Clear colourless or amber, type 1, glass ampoules in packs of 10.

STORAGE INSTRUCTIONS:
Protect from heat and light.
Store below 25°C. Do not refrigerate.
KEEP OUT OF REACH OF CHILDREN.

Name of DrugDiclofenac Sodium InjectionBatch No.080606
Mfg. Date:08/2016Exp. Date08/2019
Sampling date25/08/2016Report date01/09/2016
Specification75mg/3ml×10Amps/Box

Quantity

30000 Boxes
Standards:National Standard
ITEM
STANDARDS
RESULTS
Characteristic:A clarity and colorless solutionComplies
Identification:Should Positive reactionPositive reaction
Clarity of solution:Meet the requirementComplies
Color of solution:Meet the requirementComplies
pH:7.5~9.08.3
Sterility:Should SterilityComplies
ASSAY:C14H10Cl2NNaO293.0%~107.0%98.7%


Quality Anti-inflammatory ,analgesic,antirheumatic,antipyretic  Diclofenac Sodium Injection 75mg/3ml 10 ampoules for I.M/I.V use for sale
Send your message to this supplier
 
From:
Enter your email please.
To: Wuhan uni-pharma bio-tech co.,ltd
Subject:
Message:
Characters Remaining: (0/3000)
 
Inquiry Cart 0
  • Haven't found right suppliers
  • Our buyer assistants can help you find the most suitable, 100% reliable suppliers from China.
  • And this service is free of charge.
  • we have buyer assistants who speak English, French, Spanish......and we are ready to help you anytime!
  • Submit Buying Request
    Contact Us Quickly